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Alexey A. Loshin, Alexander D. Smolenkov, Oleg A. Shpigun
Porous
polymeric substrates based on styrene-divinylbenzene copolymer for reversed
phase and ion-chromatography
Abstract
The current review is
devoted to the polymeric substrates based on styrene-divinylbenzene copolymer
(PS-DVB) widely utilized as stationary phases in high performance liquid
chromatography (HPLC) due to their high mechanical and chemical stability.
PS-DVB material could be used as stationary phase without modification in
reverse phase HPLC-mode (RP), and as anion-exchanger in ion chromatography (IC)
after multistage surface functionalization (in order to increase the
selectivity and efficiency). The first chapters of the review consider various
production processes of PS-DVB substrates for HPLC, their main structural
physical and chemical characteristics, as well as various methods for analyzing
the surface and porous structure. There are quite a few review articles in the
scientific literature considered the synthesis and properties of organic
polymer material. However, there is practically no data on the correlations
between polymer characteristics and the chromatographic performance of the
stationary phases in HPLC. Therefore the aim of the review is to investigate
the interdependencies between the parameters of PS-DVB substrates (particle
size, specific surface area, pore size) and the chromatographic performance of
stationary phases in HPLC.
Key words: review, synthesis of stationary phases, porous polymeric
substrates, polystyrene-divinylbenzene, reversed-phase chromatography, ion
chromatography
Copyright (C) Chemistry Dept., Moscow State University, 2002
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