|
Anan’eva I. A., Shapovalova Ye. N., Lopatin S. A., Shpigun O. A., Varlamov V. P., Davankov V. A.
Separation of
Enantiomers of Amono Acid Derivatives on Amono-b-Cyclodextrin by
High-Performance Liquid Chromatography
Abstract
Chromatographic
behaviour of optical isomers aminoacid derivatives with different modifiers on
amino-b-cyclodextrin
bonded on silica was studied. Discrimination ability for this column depends on
structure of modifiers and existence of aminoacid polar groups. Influence of
various ratios methanol and buffer in mobile phase on k’ and RS was
studied. Selectivity and efficiency of this column in reversed-phase and
polar-organic phase modes for carbobezoxy- aminoacid derivatives were
estimated.
Copyright (C) Chemistry Dept., Moscow State University, 2002
|
|
