N. V. Borzenkova, I. A. Veselova, T. N. Shekhovtsova
The
possibilities of artificial receptors to enhance the selectivity of
oxydoreductase substrates determination
Abstract
Prospects of the application of molecular recognition with artificial
receptors (macrocyclic compounds and molecularly imprinted polymers) for the
creation of sensors for the determination of biologically active compounds –
oxydoreductase substrates in samples with complex matrices are discussed in
this review. Data on the preparation, properties and analytical application of
complexes of the mentioned artificial receptors with analytes – organic
compounds of different classes, are systematized for the first time. Special
attention is paid to the discussion of approaches which provide the receptor
specificity towards analytes due to molecular recognition.
Key words: oxydoreductase substrates, molecularly imprinted polymers,
macrocyclic compounds, molecular recognition.
Copyright (C) Chemistry Dept., Moscow State University, 2002
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