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I. A. Rodin, A. N. Stavrianidi, A. V. Braun, O. A. Shpigun
Modern approaches for identification and
determination of ginsenosides
Abstract
Ginsenosides are the main bioactive
compounds of the plants of Panax genus. Ginseng and its analogies are often use
in the production of traditional medicine in China, Korea, Japan, USA and Russian Far East. For more than 40 years researchers have been developing methods of
identification and determination of ginsenosides in plant materials, extracts
and commercial products. For the purification of ginsenosides from plant
materials different extraction techniques were used. Separation of ginsenosides
has been achieved using gas chromatography, thin layer chromatography and high
performance liquid chromatography (HPLC). From the list of approaches HPLC
prevailed. Spectophotometric, fluorescence, and, recently, evaporative light
scattering and mass-spectrometric detection were coupled with HPLC for the
detection of ginsenosides. The most recent methods are here discussed together
with a critical evaluation of the published results.
Key words: ginsenosides, Panax ginseng,
HPLC, bioactive compounds.
Copyright (C) Chemistry Dept., Moscow State University, 2002
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