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P. O. Bochkov, A. I. Revelskiy, I. V. Guljaev, E. V. Blynskaya
Definition of afobazole and its basic
metabolites a method of a capillary gas chromatography–mass spectrometry
Abstract
The possibility of the analysis of target
compounds is shown by method GH/MS, and also their structure are confirmed. The
possibility of sorption of investigated compounds in chromatographic
system is analysed. The results of various ways of input of the probe in an
analytical column are compared. The high-sensitivity method of the analysis is
developed for definition of microquantities of defined compounds. Limits of
detection of investigated compounds were 5.10–10 g in
probe of a modeling solution.
Key words: afobazole, metabolites, a
capillary gas chromatography, mass spectrometry, great volume of tests.
Copyright (C) Chemistry Dept., Moscow State University, 2002
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