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A. N. Mikhalyuk, E. N. Shapovalova, A. G. Maguga, O. A. Shpigun, P. G. Rudakovskaja
Separation of nitrogen-contaning compounds
on silica capillaries modified with citrate- stabilized gold nanoparticles,
6,10-ionene, n-(3-sulfo-3 carboxy)propionilechitosan and dextran sulphate
Abstract
Gold nanoparticles are applied in different
fields of science for a last 10 years, e.g. physicochemical separation methods.
Two fused-silica capillaries for capillary electrophoresis (CE) modified
layer-by-layer with citrate- stabilized gold nanoparticles, 6,10-ionene,
N-(3-sulfo-3-carboxy)propionylchitosan (SCPH) and dextran sulfate (DC) are
prepared and investigated. It is found out that separation of tetrahydrosoline,
pindolol, terbutalin, nadolol, hydroxyzine is most effective and fast in case
of modifying with gold nanoparticles and polysaccharide in comparison with case
of polysaccharide only. The most successful system for CE with utilization of
dextran sulfate as polysaccharide is received. The enantiomers of tetrahydrozoline
are separated on capillary modified with gold nanoparticles, 6,10-ionene and
dextran sulfate.
Key words: capillary electrophoresis,
dextran sulfate, N-(3-sulfo-3-carboxy)propionylchitosan, β-blockers.
Copyright (C) Chemistry Dept., Moscow State University, 2002
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