O. I. Vernaya, V. P. Shabatin, A. M. Semenov, T. I. Shabatina
Cryochemical synthesis and antibacterial
activity of hybrid composition based on ag nanoparticles and dioxidine
Abstract
Hybrid nanocomposites based on dioxidine
antimicrobial substance, modified by silver were produced by means of
cryochemical synthesis. TEM, UV-absorption spectroscopy, X-ray
diffraction, surface analysys based on low temperature
argon adsorbtionshowed the formation of hybrid nanosystems
consisting of drug substances particles with the size of 50–300 nm including
inside small Ag nanoparticles with the size of 2–40 nm. Obtained hybrid nanosystems
showed higher antibacterial activity against E. coli 52, S. aureus
144 and M. cyaneum 98 than original drug.
Key words: silver nanoparticles,
dioxidine, cryochemical synthesys, hybrid
materials, nanocomposites.
Copyright (C) Chemistry Dept., Moscow State University, 2002
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