|
Z. G. Denieva, N. A. Romanova, T. G. Bodrova, U. A. Budanova, Yu. L. Sebyakin
Synthesis of
amphiphyl peptidomymetics based on aliphatic derivatives of natural amino acids
Abstract
This work is aimed at creating several
derivatives of lipoamino acids based on L-serine, L-ornithine and L-lysine with
potential antibacterial activity. The developed synthesis schemes are
distinguished by the simplicity and versatility of the proposed approach. It is
allows them to be used in preparing a series of samples in preparative
quantities necessary for the subsequent physical, chemical and biochemical
studies.
Key words: antibacterial activity,
lipoamino acids, aliphatic L-serine derivatives, L-lysine, L-ornithine,
cationic amphiphiles.
Copyright (C) Chemistry Dept., Moscow State University, 2002
|
|
