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P. S. Novikov, N. A. Cherevko, S. E. Kondakov, E. S. Ihalainen
Evaluation of the mineral status in
patients with food hypersensitivity and metabolic disorders
Abstract
The paper considers the role of mineral
elements in patients with food hypersensitivity with an assessment of their
contribution to the development of metabolic disorders. In the course of the
study, a comparative analysis of the concentration of 29 macro- and
microelements with a simultaneous assessment of immunological and biochemical
parameters in patients with an increased body mass index was compared with
volunteers with a normal body mass index. We established relationships between
serum lipid profile and lead (Pb) concentration in hair samples: Pb and
cholesterol (Rs = 0.38; p < 0.05), Pb and LDL (Rs =
0.33; p < 0.05), Pb and atherogenicity index (Rs = 0.34, p <
0.05). An inverse correlation was found between serum IL-6 concentrations and
zinc in hair samples (Rs = –0.45, p < 0.05), as well as
a correlation between milk hypersensitivity and calcium (Ca) concentration in
hair samples: Ca and IgG to casein (Rs = –0.54; p <
0.05), Ca and IgG to cow’s milk (Rs = –0.36; p < 0.05),
Ca and IgG to cottage cheese (Rs = –0.52; p < 0.05).
The results of this work show the role of macro- and microelements as significant
predictors in the development of metabolic disorders.
Key words: macro- and microelements, food
hypersensitivity, metabolic syndrome, chronic inflammation.
Copyright (C) Chemistry Dept., Moscow State University, 2002
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