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Alexander S. Gubin, Aleksei A. Kushnir, Pavel T. Sukhanov
Application of matrix solid-phase
dispersion combined with gas chromatography–mass spectrometry for the
determination of bisphenol A in fresh-water fishes
Abstract
Abstract. Matrix solid-phase dispersion
using of a humate-based magnetic sorbent is proposed as an efficient method for
the concentration of bisphenol A from fish muscular and hepatic tissue samples
followed by the chromatography-mass spectrometry determination of analyte
pre-derivatized with acetic anhydride. Under the optimum concentration
conditions (the stirring time was 10 min and the sorbent weight was 0.05 g),
the recovery of bisphenol A upon single sorption reached 85%. The percentage
desorption exceeded 99% (the eluate was methanol, the time was 3 min, and the volume was 1
mL). The maximum concentration factor was 718. The limit of detection of
bisphenol A was 0.15 μg/kg (on dry basis) for
the muscular tissue and 0.25 μg/kg for liver.
Key words: bisphenol A, matrix solid-phase
dispersion, GC-MS, magnetic sorbents, fresh-water fishes, determination
Copyright (C) Chemistry Dept., Moscow State University, 2002
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