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Elena A. Gorbunova, Nikita E. Kononenko, Yana N. Korovkina, Tatiana V. Dubinina, Elena R. Milaeva
Synthesis and properties of functionally
substituted phthalocyanines: from photocatalysis to photodynamic therapy
Abstract
Abstract. The review is devoted to the main
methods for obtaining functionally substituted phthalocyanine complexes, as
well as the initial precursors – phthalonitriles containing various hydrophilic
and hydrophobic groups. A comparison of the optical and photochemical
properties of phthalocyanines is presented, including the directions of
generation of active oxygen metabolites. The areas of application of
phthalocyanines are designated: photocatalysis, fluorescent diagnostics,
antitumor and antibacterial photodynamic therapy.
Key words: phthalocyanines, medicinal chemistry,
photodynamic therapy, reactive oxygen metabolites, spectroscopy, fluorophores
Copyright (C) Chemistry Dept., Moscow State University, 2002
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