|
Bogush T. A., Lee A., Kalyuzhny S. A., Bogush E. A., Melnikov M. Y., Kosorukov V. S.
TUBB3 expression in non-small cell lung cancer: the reason for
immunohistochemical assay discordance and the way to overcome it
Abstract
Abstract.
Discordant data on TUBB3 microtubule protein contribution to antitumor
drug resistance and tumor metastatic potential as well as TUBB3 expression
prognostic value in non-small cell lung cancer, have been analyzed. The need of
quantitative assessment methods, in particular, immunofluorescence assay
associated with flow cytometry, as a component of molecular diagnostics, is substantiated.
Key words:
TUBB3, non-small cell lung cancer, immunofluorescence analysis, flow cytometry,
immunohistochemical analysis
Copyright (C) Chemistry Dept., Moscow State University, 2002
|
|
