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Ilya V. Grigoryan, Vasily V. Spiridonov, Artyom M. Adelyanov, Yuri A. Koksharov, Kirill V. Potapenkov, Igor
V. Taranov, Gennady B. Khomutov, Alexander A. Yaroslavov
New
magnetic colloidal systems based on biomimetic polycomplexes
Abstract
Abstract. This paper presents new colloidal systems that have prospects for
use as carriers of medicinal compounds and are polymer complexes based on
polyacrylic acid molecules of various molecular weights and biogenic polyamine,
additionally modified with magnetic iron oxide nanoparticles. The main
physicochemical characteristics of the resulting polycomplexes were determined.
The possibility of incorporating the drug compound doxorubicin into
polycomplexes was demonstrated and the magnetic properties of polycomplexes
functionalized with magnetic iron oxide nanoparticles were studied.
Key words: polymers, polycomplexes, spermine, magnetic nanoparticles,
colloidal system
Copyright (C) Chemistry Dept., Moscow State University, 2002
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